Psychiatry Psychiatry and psychopharmacotherapy named after. P.B. Gannushkina No. 01 1999

The modern rhythm of life negatively affects health and sometimes causes a malfunction of the autonomic nervous system. Sedatives will help restore its functioning and normalize the lost balance in the body. In such cases, Novopassit or Persen are often taken.

Novopassit or Persen will help normalize the lost balance in the body.

Pharmacology

Tablets are a medicinal product with a sedative and antispasmodic effect. Melissa, valearian and mint extract provides a calming and antispasmodic effect.

In general, after taking the drug there is a decrease in feelings of anxiety and nervousness. There is a noticeable improvement in the condition of people in an excited and emotional state. With insomnia, the patient falls asleep much easier and faster, sleeps more soundly, and does not feel drowsy throughout the day.

Persen has a general effect on the human body due to its constituent components. Therefore, no clinical studies have been conducted. It is not possible to determine the metabolites of the drug.

Safety

Both drugs are medicines made from plant materials. Thus, a fairly high safety of both drugs is achieved, but their composition should be considered in more detail.

— In general, Novopassit has more components, there are eight of them (valerian, lemon balm, hawthorn, hops, elderberry, St. John's wort, passionflower and the non-herbal component guaifenazin). — Persen contains only three components – valerian, lemon balm, mint.

The main contraindication and one of the most common side effects (typical of any herbal preparations) is an allergic reaction. It is logical to assume that Novopassit with a large number of components has a high risk of developing allergies. Also, the existing non-herbal component has contraindications for use such as the presence of a gastric ulcer, a history of bleeding and side effects in the form of diarrhea, gastralgia and other problems with the gastrointestinal tract.

Instructions for use

The tablets are intended for internal use. Can be taken at any time, regardless of meals. You need to drink enough water.

From 12 years old you can take 2 tablets 2 times a day. The attending physician will be able to prescribe the correct course of treatment.

If a person has insomnia, then you need to take 2 tablets in the evening an hour before bedtime. The maximum permissible dosage is 12 tablets per day.

The duration of continuous treatment should not exceed more than 45 days. After finishing taking the pills, withdrawal symptoms do not appear.

Efficiency

As we already said in the previous article about comparing drugs, it is difficult to predict the effect of a particular drug. However, several assumptions can be made. Two of the three components of Persen are also present in the competitor, however, in addition to this, it has five more active ingredients. Therefore, in terms of efficiency, we still give the palm to Novopassit. It is also worth saying that the effectiveness of Persen can be partially verified in the following way. Try brewing valerian herb or taking a few tablets of regular pharmacy valerian. If there is no effect at all, then, most likely, the effect of Persen will also be low. The combination of all of the above properties will ultimately affect adherence to therapy, because the dosage regimen is similar (1-2 tablets three times a day).

We can discuss for a long time various aspects of competitors: the ability of Novopassit to reduce the effectiveness of hormonal contraception, the ability to drive a vehicle while using Persen and the restriction on that of another drug, the likelihood of developing constipation when taking Persen Forte. However, the conclusion of the article, to the probable regret of readers, will be different. Before using these sedatives, it is difficult to predict which one is best for a particular person. No full-fledged studies aimed at identifying the degree of effectiveness of drugs or assessing them according to other criteria have been carried out. When choosing, you can focus on the above pros and cons, and make decisions based on what is more important for you specifically.

Adverse reactions and overdose

When taking pills, negative reactions may occur in the form of:

  • allergies, manifested by hyperemia, bronchospasms and skin rash;
  • Long-term use may cause constipation.

Cases of overdose are possible. Usually happens if more than 60 tablets have been taken. Nausea, vomiting, lethargy, pain inside the body, and dizziness may occur. 24 hours after taking the drug in large quantities, the signs of overdose disappear. No toxic effects are observed. If necessary, you can do symptomatic treatment.

Which is better - Novopassit or Persen

Each of the medications has an effective sedative effect on the body and helps eliminate disturbing symptoms.

Each of the medications has an effective sedative effect on the body and helps eliminate disturbing symptoms.

The choice of a therapeutic agent must be approached individually, based on the result and your internal feelings. Due to the difference in composition, drugs may be tolerated differently by the body and have different side effects.

Recommended reading: What to choose: Metoprolol or Bisoprolol?

Other information

The drug should be stored at room temperature. Shelf life – 36 months from the date of release. Sold in pharmacies without a doctor's prescription.

Before taking Persen, you need to familiarize yourself with the features of its action and in what cases the tablets will be effective. If during therapy the symptoms do not disappear or the condition becomes even more severe, then you need to seek help from a specialist.

In patients with gastroesophageal reflux disease, the condition may only worsen during treatment.

After taking the pills, it is better to stop driving a vehicle and other dangerous mechanisms.

The duration of the treatment course should not exceed 60 days. If negative reactions occur, you should immediately inform a specialist.

Compound similarities

The similar medicinal properties of drugs are due to their composition. The presence of 2 main common components gives an almost identical effect when treated with drugs.

We recommend reading: Why is Voltaren prescribed for inflammation of the thyroid gland?

Valerian extract has a diverse effect on the body. As a result of its use, positive changes occur in the functioning of many organs and systems:

  • Digestion is improved, the functioning of the intestinal tract is normalized, bile secretion increases;
  • blood vessels dilate, cardiac activity improves;
  • emotional balance is restored, the level of worry and anxiety is reduced, and performance increases.


Melissa extract relieves spasms and has a stimulating effect on brain function. The calming effect of the herb on the body leads to the elimination of headaches and migraines, and normalization of sleep.

Introduction

The drug Novo-Passit has been in service with our doctors for more than 10 years and has rightfully won its rightful place among sedatives due to its effectiveness, the possibility of use in a wide variety of age groups, the absence of any side effects, high ansiolytic activity and, finally, very important for its accessibility.
Unfortunately, despite the significant experience accumulated by our psychiatrists and general practitioners in the domestic medical literature, we find a relatively small number of publications about this drug. We will try to fill this gap, following the wishes of our readers, especially since the tablet form of the drug will go on sale this year.

Composition of the drug Novo-Passit: solution Guaifenesin 4.0 (in 100 ml), plant extract Passit 7.75 g.

Reviews from doctors

Valery (therapist), 43 years old, Moscow

The sedatives Novopassit and Persen, which have natural ingredients in their composition, are practically safe for health. They effectively reduce the excitability of the nervous system and eliminate spasms in muscles and organs.

Olesya (neurologist), 47 years old, Ufa

There is a positive effect of these drugs on the heart and normalization of sleep. During treatment, the balance of excitation and inhibition processes in the body improves. But at the same time, it is necessary to comply with all medical recommendations, because Even as a result of using natural medicines, side effects may develop.

What are the consequences of using Phenazepam with alcohol?

Phenazepam can be used as a complex treatment for alcoholism to relieve withdrawal symptoms. A prerequisite for successful treatment is complete abstinence from drinking alcohol. If a person does not follow the doctor’s recommendations and continues to drink alcohol, the following consequences are possible:

  • confusion;
  • slowing down the respiratory rate;
  • development of bradycardia;
  • dyspnea;
  • feeling of lack of air;
  • decreased blood pressure;
  • pronounced tremor;
  • drowsiness;
  • speech disorders;
  • lack of coordination of movements;
  • very tired.

In the presence of concomitant pathologies and due to an overdose of Phenazepam, the joint use of alcoholic beverages can lead to death.

Alcohol consumption also increases the likelihood and severity of side effects:

  • memory and intelligence impairment;
  • psychomotor agitation;
  • attacks of anger and aggression, increased irritability;
  • hallucinations;
  • suicidal thoughts;
  • severe insomnia;
  • severe headaches;
  • uncontrollable vomiting;
  • liver damage;
  • damage to the urinary system.

Active ingredient: guaifenesin

The use of guaifenesin in therapy began at the end of the last century, when its antiseptic effectiveness was discovered; its expectorant effect was discovered later. After the Second World War, the substance began to be used as a muscle relaxant and in the field of psychiatry. Guaifenesin was first tested in psychiatry by Frankl, and then by Leventhal and Ringl in 1952. A year later, the results of therapy with guaifenesin were published by Leinart. The results of these studies confirmed its high effectiveness in anxiety states accompanying various mental illnesses.

Guaifenesin mainly affects neurotic disorders. It was found that it has the greatest effect on anxiety, especially of neurotic origin (effect in 80% of patients). To a lesser extent - on a state of anxiety, accompanied by obsessive ideas.

It also eliminates fears, especially those associated with upcoming unpleasant events (exams, painful medical procedures, etc.).

Another potential area of ​​clinical use for guaifenesin is headaches. Guaifenesin eliminates the main cause of psychogenic etiology (anxiety, tension), as well as increased muscle tone in the craniocerebral region.

Considering its excellent effect on the state of psychogenic tension with vegetative symptoms (palpitations, shortness of breath, insomnia, headaches), a number of Czech psychiatrists (M. Zapletalek and others) recommend it for the so-called. “manager disease”, i.e. for people working in a state of constant stress in leadership positions.

The drug is non-toxic, with virtually no side effects. Isolated cases of allergic dermatoses have been observed, as well as mild muscle weakness (Smith, Carraza, Ginrel).

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