Dependence on sedatives and sedatives


Sleep disturbance is a common problem that plagues people of any gender and age. If in youth this phenomenon can be associated with fatigue, nervous tension or psychosomatics, then in old age poor sleep is considered the norm.

To extend their rest, people use sleeping pills, which are most often self-prescribed. Such a careless attitude towards health can play a cruel joke, and the lack of effect of a medicine for insomnia is the most harmless of the possible consequences.

The best sedatives for the nervous system.

October 8, 2021
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Content
  • How to choose a sedative
  • Top 10 safe sedatives
  • Dormiplant
  • Magnesium-Diasporal
  • Persen
  • Avexima Dobrokam
  • Novo-Passit
  • Positive
  • Stressovitis
  • Tenoten
  • Afobazole
  • Motherwort Forte Evalar

Today's rhythm of life is a constant cycle of events, a “race”, during which each of us strives to complete a lot of tasks. Hence the eternal stress. And if we add here financial instability, problems in the family or at work... Often the nervous system simply cannot cope, which is fraught with neuroses and depression.

If you feel that you can’t cope on your own, and your nervous system is becoming more and more unstable every day, be sure to consult a doctor (neurologist, psychiatrist or psychologist) - he will select a sedative that will eliminate the problem and prevent negative consequences from developing.

Features of insomnia treatment

The sleep that sleeping pills induce usually differs from natural, physiological sleep. This is especially true for reducing the duration of REM sleep.

With the abrupt withdrawal of sleeping pills, the time for the onset of REM sleep is shortened for a certain time, and REM sleep itself is lengthened, that is, the so-called “recoil” phenomenon develops. This manifests itself in the fact that the patient begins to see a large number of nightmares, which in turn lead to frequent awakenings.

Sleeping pills have different effects on sleep patterns. Derivatives of barbituric acid change the structure of normal sleep the most, and benzodiazepine derivatives the least. Zopiclone, zaleplon and zolpidem practically do not change the structure of sleep (which makes them almost “ideal” sleeping pills).

All sleeping pills enhance the effect of other drugs that depress the central nervous system - sedatives, antipsychotics, tranquilizers, anticonvulsants.

How to choose a sedative

Our list of nerve pills are over-the-counter medications that are prescribed for minor stress, have a gentle effect on the nervous system and mostly contain natural ingredients. Typically, such medications are used for mild insomnia, when a person is nervous before an important event, for problems at work, in his personal life - in general, with increased emotional stress. But if, during treatment with sedatives, anxiety does not go away after a week or two, you need to consult a doctor again - he will prescribe stronger drugs.

Plant-based sedatives (such as Persen, Novo-Passit) are indicated for patients with temporary anxiety. If a person is under stress for a long time and feels negative symptoms, but there is no reason for this, it is necessary to check the thyroid gland, donate blood for anemia, vitamin D, and undergo tests for anxiety disorders and depression. In parallel with taking sedatives, it is important to learn relaxation techniques and talk to a psychologist to work through your anxious thoughts. Read also: Top 5 drugs for insomnia that are sold without a prescription The best over-the-counter drugs for the treatment of insomnia

Neuroleptics

When trying to classify antipsychotics, scientists primarily rely on their chemical structure:

  • aliphatic phenothiazines - drugs whose antipsychotic activity is weakly expressed, they are aimed at sedation (calm down, help to sleep);
  • butyrophenones (popular haloperidol) are powerful antipsychotics that have almost no sedative effect, they stop hallucinations and delusions;
  • dibenzazepines have mild side effects, are better combined with other drugs, but have almost no sedative effect, and are aimed at relieving psychotic manifestations;
  • Phenothiazine derivatives relieve pain and are prescribed for damaged blood vessels and thrombophilitis.

Neuroleptics or antipsychotics are atypical or typical, long-acting or non-long-acting. Typical antipsychotics are outdated drugs that do an excellent job of relieving psychotic symptoms, but have a high likelihood of side effects. Atypical is a modern version of antipsychotics that reduces the risk of side effects to a minimum. Long-acting antipsychotics have a long-lasting effect, their effect is noticeable for 20-30 days. They are not taken daily.

Neuroleptics eliminate severe fear, anxiety, agitation, and improve sleep. They are used for severe psychotic depression, the dosage is low. Neuroleptics are prescribed more often to patients with psychoses combined with psychomotor agitation. Less commonly used for apathy and lethargy.

Prescribing antipsychotics to children is a controversial issue in psychiatry. There is a lack of evidence-based medicine on this issue. Therefore, antipsychotics are prescribed to pediatric patients, but rarely, with caution and in small dosages.

Dormiplant

A sedative made in Germany, which contains valerian and lemon balm. Dormiplant helps well with increased nervous excitability and problems falling asleep. Contraindications include intolerance to the components of the drug, as well as liver failure. Dormiplant tablets are easy to swallow because they are not very large, round, with beveled edges. You need to take sedative tablets twice a day (morning and evening), 2 pieces, regardless of meals. Those who have taken this remedy write that Dormiplant is an excellent help for sleep problems. And if a person gets full rest at night, then during the day he is less irritable and is in a good mood. Dormiplant is often prescribed by neurologists for severe stress. Sometimes patients have adverse reactions - nausea and abdominal pain.

Dormiplant
Dr. Willmar Schwabe, Germany

increased nervous excitability;
insomnia (difficulty falling asleep). from 407

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When is drug treatment for insomnia necessary?

Many therapists and neurologists make one very common mistake, which, unfortunately, often leads to dire consequences. When complaining of problems with sleep, sleeping pills are immediately prescribed, and if there is no effect from their use, few people think about the reasons for this phenomenon - they simply prescribe more potent pills for insomnia.


But the specialists of the Leto clinic practice a completely different approach. We pay great attention to examining the patient and identifying the cause of insomnia. As practice shows, in many cases, sleep disturbances are caused by factors that can be easily eliminated without medication.

When collecting anamnesis, doctors often find out that a person neglects his daily routine, in the evenings, lying in bed, playing on a smartphone until late, reading forums, watching videos, etc. Not the least important role is played by the quality of bed linen, pillows, mattresses, lighting, humidity, temperature in the bedroom, and sound insulation. And in the vast majority of cases, within a couple of weeks after correcting the daily routine, diet, and improving rest conditions, all sleep problems go away without taking any medications.

Another cause of insomnia is concomitant diseases, which are accompanied by chronic pain (for example, damage to the musculoskeletal system), an extremely unpleasant sensation of pulsation in the temples, chest, head, tachycardia (these are the majority of cardiovascular pathologies), and frequent urination, for example, with chronic cystitis. In such a situation, first of all, doctors treat the underlying disease, and drugs for insomnia are prescribed for a short period.

Indications for drug therapy

  • a person rolls around in bed for at least half an hour before falling asleep;

  • frequent awakenings at night, due to which the duration of rest is reduced by 30 minutes or more;
  • waking up early in the morning 1–3 hours before the alarm goes off;
  • due to insomnia, daily activities are disrupted: due to constant drowsiness and feelings of fatigue, a person is forced to limit daytime activity, performance decreases, concentration deteriorates, absent-mindedness and forgetfulness appear;

The listed disorders are the basis for prescribing drug therapy in the following cases:

  • the patient has all the opportunities and conditions for sleep;
  • problems occur at least three times a week;
  • insomnia is not explained by the presence of another disease.

Magnesium-Diasporal

This is a mineral complex to strengthen the nervous system and heart health. The drug contains 300 mg of magnesium, which completely covers the daily requirement of this mineral in the body. “Magnesium-Diasporal” is presented in the form of a powder, which must be dissolved in water, juice, tea, or simply poured into the mouth and washed down. Take this sedative once a day, regardless of food. The complex helps well with increased anxiety, problems falling asleep, aggression, increased fatigue, muscle cramps and cardioneurosis. Contraindications include age under 12 years, renal failure, breastfeeding (Magnesium-Diasporal is often prescribed to pregnant women to reduce the tone of the uterus and relieve irritability). It is a safe sedative, but its effect is temporary and it is expensive.

Magnesium-Diasporal
Protina Pharmazeutische GmbH, Germany

Indications for the drug Magnesium-Diasporal 300 are magnesium deficiency, accompanied by symptoms such as minor sleep disturbances, increased irritability, mild anxiety, increased fatigue, spasms of the calf muscles.
from 199

5.0 8 reviews

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Persen

A sedative that has long been prescribed by doctors and has proven itself to be excellent. Persen contains three active ingredients: mint, valerian and lemon balm. They soothe and relieve spasms. Persen is prescribed for insomnia, increased nervous agitation, irritability, and sleep problems. It should be borne in mind that these nerve pills are not suitable for people with low blood pressure and those who have problems with the biliary tract. The tablets are easy to swallow and can be taken with or without food. Dosage – 2-3 pieces per day. For insomnia, you need to take Persen an hour before bedtime, 2-3 tablets. The drug has a cumulative effect, it is safe, and has no withdrawal effect. A sedative helps eliminate the “nervous lump” in the throat. Rare side effects include allergic manifestations, constipation and bronchospasm.

Persen
Lek d.d., Slovenia

A sedative of plant origin, which is used for: increased nervous excitability;
- insomnia; - irritability; - depressive states; - panic disorders. from 192

5.0 1 review

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How to overcome insomnia?

Both medicinal and non-medicinal methods are used to treat insomnia:

  • maintaining sleep hygiene;
  • psychotherapy;
  • physiotherapy, massage;
  • relaxation techniques, breathing exercises, etc.

For acute insomnia, specific treatment is usually not required; removing the trigger that prevents you from falling asleep is sufficient. Chronic and short-term forms of insomnia are important to monitor together with your doctor. The specialist will determine the cause of insomnia and, if necessary, prescribe a course of sedative or hypnotic medications. These can be herbal medicines (Persen, Novo-Passit, etc.), melatonin-based medicines (Melaritm, Melaxen, etc.) or more serious prescription medications.

The drugs have contraindications. The attending physician should prescribe the drug and determine the dosage.

Avexima Dobrokam

An excellent safe psycholeptic prescribed for sleep problems. "Avexima Dobrocam" contains 250 mg of bromcamphor and is prescribed for increased nervousness, tachycardia, pressure surges, insomnia and cardialgia. You can buy Avexima Dobrocam without a prescription; in small doses it is indicated even for children over 7 years old and pregnant women. Typically, the course of treatment with this sedative lasts two weeks (1-2 tablets three times a day). You cannot exceed the dosage on your own, because your body temperature may increase, convulsions and breathing problems are possible. While taking Avexima Dobrocam, the speed of reactions decreases, so it is better to avoid driving a car.

Dobrokam
Irbitsky Chemical Plant, Russia

- increased excitability;
- asthenia; - cardialgia; - tachycardia; - lability of blood pressure. from 147

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Novo-Passit

Another well-known plant-based sedative, which contains 7 medicinal plants: hops, St. John's wort, lemon balm, elderberry, valerian, hawthorn, passionflower, and guaifenesin (a substance that reduces anxiety). Novo-Passit has a complex effect: it suppresses anxiety and calms. The drug is prescribed for increased mental fatigue, sleep problems, nervous overexcitation, and mental stress. You need to take Novo-Passit three times a day, 1 tablet (usually before meals). If apathy and fatigue are felt while taking a sedative, the morning and daily dose can be halved. The interval between taking tablets should be at least 4-6 hours. In reviews, many people write that Novo-Passit begins to act almost immediately after the start of treatment. An important plus is the absence of drowsiness, lethargy and apathy, as well as the withdrawal effect. There are practically no side effects with Novo-Passit, rarely problems with digestion.

Novo-Passit
IVEX Pharmaceuticals, Czech Republic; Teva Pharmaceutical Industries, Germany

Novo-passit is a combination drug, the pharmacological activity of which is due to its constituent components of an extract based on medicinal plant raw materials with a predominantly sedative (calming) effect and guaifenesin, which has an anxiolytic (anti-anxiety) effect.
from 161

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Symptoms of stress

Photos from open sources

What happens if you take sleeping pills with alcohol?

  • Stopping breathing during sleep, which can lead to death.
  • A sharp drop in pressure to a critical level.
  • Severe weakness and apathy.
  • Slowness of movements and reactions.
  • Slowing heart rate.
  • Dizziness and headache.
  • Aches in the joints.
  • Exacerbation of mental disorders that were previously present or developed against the background of excessive abuse of alcoholic beverages.

If you cannot do without the use of special means, then before using them you should consult a doctor to determine which sleeping pills you can take with alcohol. Such drugs are available in pharmacies today, but the selection in each specific case must be carried out by a specialist.

Positive

A herbal multi-component sedative to improve the functioning of the nervous system under increased psycho-emotional stress. The drug “Positive” is prescribed for causeless anxiety, prolonged stress, to improve mood during the day and for insomnia at night. The Positive capsules contain eleutherococcus, ginseng, and ginkgo biloba. All these natural ingredients have a gentle effect on the nervous system. The drug should be taken in the morning with food, the course of treatment is two weeks (can be repeated after 1-2 months). Contraindications include serious heart problems, hypertension, and pregnancy.

Positive
V-MIN+, LLC, Russia

As a food supplement - a source of tryptophan, eleutherosides, panaxosides, flavonoids, an additional source of selenium, vitamins (B6, B12, folic acid), containing 5-hydroxytryptophan.
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Stressovitis

Natural sedative based on motherwort, linden, hops, vitamin B6 and magnesium. An excellent drug for those who are in a stressful situation, regularly experience nervous overload, feel irritability, unreasonable anxiety, and restlessness. You need to take only one Stressovit capsule per day with food. The course of treatment is 2-3 weeks. After a month you can repeat the course. Judging by the reviews of those who took Stressovit, the drug has a cumulative effect, it is well tolerated and has no side effects.

Stressovitis
Unifarm, USA

Stressovit is a complex biologically active remedy for reducing psycho-emotional stress, restoring the nervous system, relieving stress and increasing performance.
from 350

5.0 2 reviews

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The most effective drugs

The best remedy for insomnia is the one that does not cause side effects and solves the problem, it varies from person to person. Due to the individual characteristics of the body and health status, it is necessary to be diagnosed in a hospital before starting treatment. Otherwise, what suited your neighbor or friend may not only have no effect on you, but also lead to a number of deviations.

Depending on the degree and nature of sleep disorders, doctors most often prescribe the following remedies, which can be purchased at the pharmacy.

NameDescriptionprice, rub.
"Fitosedan"The completely herbal composition promotes relaxation, quick falling asleep, and elimination of tachycardia. Available in the form of tea bags that need to be brewed and drunk in 15 minutes. before bedtime. Allowed after a stroke. 70
"Persen"Liquid sedative based on herbs (available in the form of syrup, drops, tablets). Relaxes tense muscles and the nervous system - this is often enough for older people to quickly fall asleep. Not recommended for bile duct problems. 235
"Afobazol"It is a mild tranquilizer and is prescribed for serious sleep disorders accompanied by anxiety and stress. Does not cause addiction, does not interfere with mental and physical activity. It acts quickly and has no contraindications. 289
"Melaxen"Take 30 minutes before. before bed to normalize biorhythms. If you are hypersensitive to any of the components, reduce the intake to half a tablet. 531
"Donormil"A synthetic fast-acting drug in the form of effervescent tablets and pills with a pronounced sedative and hypnotic effect. The period of action is about 8 hours, after which the drug is completely eliminated from the body. 141
"Novo-Passit"A proven herbal sedative. You can take syrup or tablets before bed. Effectively relaxes and is not addictive. 200
"Zolpidem"A quick-acting drug prescribed after a stroke. One of the advantages is that, in addition to insomnia, it solves many other health problems (restores the activity of nerve cells, relieves seizures). The downside is that it has many contraindications. 1650
"Barboval"Odorless and tasteless sleeping pills in drops. Contains phenobarbital, bromisovaleric acid ester, validol. Suitable for sleep disorders, irritability, heart pain. Reduces blood pressure in hypertension, helps get rid of cramps, flatulence, and normalize the functioning of the digestive tract. 80
"Sondox"A new generation of fast-acting sleeping pills is available in tablets. Has a strong effect. You may experience dizziness in the morning; it is not recommended for people prone to constipation. 150
"Notta" and "Passidorm"Representatives of the homeopathic group put to sleep no worse than their analogues. Do not provoke daytime drowsiness, dizziness or inhibition. They have a mild effect and are harmless. 219/ 450

Almost all of these drugs can be easily purchased in Moscow and other cities of Russia and neighboring countries at affordable prices without a prescription. The cost may vary depending on the city and pharmacy chain.

Tenoten

Tenoten is a safe over-the-counter anxiolytic and nootropic based on antibodies to a brain-specific protein. The drug calms well, relieves anxiety, but does not inhibit or cause drowsiness. Tenoten is often prescribed for stress and the initial stages of depression. Calming lozenges are taken twice a day, 1-2 pieces. The course of treatment with Tenoten is 1-3 months. The positive effect of the medicine occurs within a couple of days after the start of treatment. "Tenoten" helps to establish normal sleep, ensures a good mood and relieves nervous tension. An important plus is the prolonged action of Tenoten: after the end of treatment, the sedative effect lasts for a long time.

Tenoten
Materia Medica Holding, Russia

TENOTEN is a calming drug with a stress-protective effect, indicated for all people with symptoms of anxiety: patients with anxiety disorders and healthy people in stressful situations.
The drug calms, relieves anxiety, irritability, nervousness, and evens out mood. Unlike other sedatives, it does not have unwanted side effects and does not have a sedative or muscle relaxant effect. In the treatment of somatic and neurological diseases, Tenoten has a vegetative-stabilizing and nootropic effect. from 152

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Read also Drugs to improve memory: neurologists recommend Drugs to improve blood circulation in the brain and memory.

Classification of sleeping pills

Sleeping pills are classified according to their mechanism of action and chemical structure:

  • Benzodiazepine receptor agonists: benzodiazepine derivatives: nitrazepam, flunitrazepam, levan;
  • drugs of a different chemical structure: zopiclone, zolpidem, zaleplon.
  • Derivatives of barbituric acid: phenobarbital.
  • H1-histamine receptor blockers: doxylamine.
  • Melatonin receptor agonists: melatonin.
  • In addition, many psychoactive substances can have a hypnotic effect. These drugs include anxiolytics (tranquilizers), certain sedatives, some antidepressants (amitriptyline) and antipsychotics (chlorpromazine), as well as antihistamines and antiallergic drugs (for example, diphenhydramine, chloropyramine, clemastine).

    Afobazole

    The active ingredient of Afobazole is fabomotizole (tranquilizer). This sedative is prescribed for autonomic disorders, anxiety, depression, and cognitive disorders. Afobazole is usually well tolerated, although it can sometimes cause headaches. Take the drug three times a day, 1 tablet after meals. The course of treatment with Afobazol is 2-4 weeks. The positive effect of the sedative occurs on the 5-7th day of treatment and persists after discontinuation of the drug for another 7-14 days. Patients write that Afobazole is well tolerated, does not cause drowsiness or decreased concentration, and does not cause muscle weakness, dependence, or withdrawal symptoms.

    Afobazole
    OJSC Pharmstandard-Leksredstva, Russia

    Afobazole is used in adults for anxiety conditions: generalized anxiety disorders, neurasthenia, adaptation disorders.
    The drug is also prescribed for somatic diseases: bronchial asthma, irritable bowel syndrome, systemic lupus erythematosus, hypertension, coronary heart disease, arrhythmias. from 204

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    Motherwort Forte Evalar

    A sedative tonic drug with a mild effect, which can be bought without a prescription. “Motherwort Forte Evalar” has been used for a long time, so it is time-tested. This natural remedy contains motherwort extract, magnesium carbonate and vitamin B6. The medicine reduces nervous tension, relieves irritability and unjustified anxiety. Motherwort Forte smoothly lowers blood pressure, works as a mild muscle relaxant, and strengthens the heart muscle. Even with prolonged use, this sedative is not addictive. Usually Motherwort Forte is taken 1-2 tablets per day with meals. Contraindications include peptic ulcer, pregnancy, gastritis during an exacerbation.

    Motherwort Forte Evalar
    Evalar, Russia

    Motherwort Forte Evalar helps to quickly relieve nervous tension and irritability, and improve emotional well-being.
    Its unique composition contains exactly that variety of motherwort, which grows in Altai and has one of the highest rates of sedation. In addition, only in Motherwort Forte Evalar the high daily dosage of motherwort (100 mg) is enhanced with the “elements of calm” magnesium and vitamin B6. from 9

    4.5 2 reviews

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