ASSESSMENT OF FUNCTIONAL ASYMMETRY USING DIFFERENT METHODOLOGICAL APPROACHES

I'll start with the medical history. During the treatment of schizophrenia with unilateral electroconvulsive shocks, which was carried out in Leningrad by a group led by L.Ya. Balanov, I had to observe such a case in the summer of 1979. A young girl, a gifted artist, does not emerge from severe delirium for months. There are so many different symbols woven into it that one of the psychiatrists, who became acquainted with the history of her illness with me, complained about the almost complete impossibility of identifying the main core in this stream of associations. After a right-sided shock, when the patient’s behavior was controlled mainly by the left (dominant in speech) hemisphere, she, answering questions, began to clearly describe the complex of sexual guilt that tormented her in front of her mother (she fancied that she had lost her innocence, although according to a medical examination, she is a girl). Before the described shock, during shocks from the opposite side, the girl (whose behavior in short intervals after the left-sided shock was controlled predominantly by the right hemisphere, which is in charge of imaginative perception) made several good drawings. After a right-sided shock, in response to a request to draw something, the girl depicted something that I could not have interpreted immediately if I had not previously studied the sexual symbolism of cave paintings of Upper Paleolithic caves (I note that these drawings are from a long period of the history of Homo sapiens characterized by schematization and focus on detail, presented as if in “close-up”, which is typical of the left hemisphere, which apparently played a special role in various types of sign activity after the victory of sound language as the main means of communication). Psychiatrists, who did not have cultural and anthropological training, did not understand the image and began to question the patient. She explained to them: “These are my genitals.” For several tens of minutes after the right-sided shock, the patient’s left hemisphere was intently engaged in introspection, the results of which we observed both in her verbal explanations and in such symbolic drawings. Then, with increasing activation of the right hemisphere, the guilt complex began to appear again in rather transformed forms of delirium, which could again seem mysterious to a new observer. While drawing, the patient said: “Paper, forgive me! Pencil, forgive me! And background, forgive me!” and fell to her knees (knocked off by the fact that she was constantly thumping on them). Concluding the story about this patient, I will add that among her schematized drawings there was also a drawing of a hand with the meaning of the symbol of God, which is characteristic of primitive art and the art of schizophrenics. I would like to emphasize that metalinguistic operations are very typical for the first hour after a right-sided shock, when the left hemisphere demonstrates all its capabilities related to language, including its metalinguistic use, in which language, turning on itself, serves as a means for its own research. Language can be used for a person to understand not only linguistic activity (normally unconscious in relation to the native language), but also for awareness of other aspects of behavior that remain unconscious without verbalization.

I will go straight to the formulation of the proposed hypothesis. Several authors in different countries dealing with functional asymmetry of the brain have independently come to the assumption that the unconscious is associated primarily with the right hemisphere, which is normally mute. In particular, many have drawn attention to the possibility of the participation of the right hemisphere in the formation of dreams (in this sense, treatment of depression through sleep deprivation in the REM phase is similar to the treatment of depression with right-sided shock). Let me add one more thing to this assumption: the conscious understanding of the sphere of gender, characteristic of an adult, belongs to the speech-dominant (left) hemisphere (and to the subcortical areas controlled by it). Penfield, when stimulating certain areas of the right hemisphere with electrodes during brain surgery, was able to evoke various unconscious memories, but they were never related to the sexual sphere. The right hemisphere is a non-speech (in certain respects “pre-speech”) repository of visual images, but images that are already transformed or infantile and do not usually contain their obvious “adult” sexual interpretation (even in those cases, it is very likely). It is advisable to proceed from the opposition of the speech hemisphere, which includes the areas of sexual life of an adult that are conscious through words, and the non-speech hemisphere, which, by the nature of its sexuality, can be infantile and reflect the pre-speech (unconscious) period of development of sexuality. The period of verbal learning about sex (normally quite long) follows the period when the child is learning his native language. It seems possible to show this in such extreme cases as “wolf” children (like Mowgli), who not only do not speak language, but also turn out to be “sexually untrained” and therefore incapable of sexual activity, and as deaf-blind people who, in the absence of special communication, for a long time (after adulthood) remain at a very infantile stage of sexual development. At the same time, the normally non-speech right hemisphere can be a source of images based on infantile and transformed (and sublimated) sexuality. It is associated with figurative creativity and with love as creativity and a source of creativity (it is enough to recall at least the circle of images that underlie the introductory stanzas to “The Knight in the Skin of a Leopard” and similar ideas in other works of medieval literature). The right hemisphere is responsible for the imagery of Pushkin’s “I Remember a Wonderful Moment,” but not for the well-known left-hemisphere author’s prose commentary on the biographical episode reflected in this poem. Blok’s personal drama, as well as the relationship between different genres of poetry (sublime, addressed to Sophia, and obscene) by Vladimir Solovyov, the originals of which, like the letters dictated to himself on behalf of Sophia, were written in different handwritings, perhaps by different hands, and this may be explained by the same difference between the figurative (infantile or sublimated suprasexual) content of emotions of the right hemisphere and the verbalized (including in cynical or erotic statements) sexual activity of the left hemisphere and the subcortical areas controlled by it. Love and creativity are normal, as well as delirium (like the case of the guilt complex with which I began), in pathology they can be correlated precisely with the right hemisphere, and sex, conscious of the mind, with the left. The left and right hemispheres are opposed as systems for controlling, on the one hand, positive emotions (up to euphoria), on the other hand, depression (which explains the possibility of its treatment with sleep deprivation or right-sided shock) and the tendency to self-destruction. In this sense, a significant danger can be posed by the uncontrolled succession of right and bilateral shocks, which can be confirmed by some examples from American clinical practice of past decades.

In a hypothetical form, one could assume that suicide (or forms of behavior close to it, for example, provoking a duel among Russian poets of the 19th century) and the Freudian “institute of death”, the role of which has received due attention only in recent times, can be linked with the right hemisphere (suicide is an extreme case, which from this point of view can be described as murder by the right hemisphere of the left). Then not only the distinction between the “I” (correlated with the left hemisphere), the “Super-ego” and the “Id” (correlated with the right hemisphere), but also the opposition of Eros (left hemisphere) and Thanatos (right hemisphere) in the late Freud could be interpreted ( in the spirit of his early experience in “Psychology for Neurologists”) from the point of view of functional asymmetry of the hemispheres.

Psychoanalysis is characterized by a focus on the word, taken to the extreme in the school of Lacan, but already embedded in the Freudian analysis of slips of the tongue and puns. If speech activity is left-hemisphere, then it is natural that during verbal comprehension (verbalization) of the unconscious, verbally conscious sexual desires as such come to the fore. But the issues of interaction between the two hemispheres and those lower levels of brain organization that are associated with them remain unresolved. Question one: we know that the subdominant (right) hemisphere uses visual gestural images, largely imprinted (through imprinting) from early childhood (when the differentiation of the functions of the hemispheres is just beginning). It remains to clarify the question posed in Freud’s letters to Fliess about how early the first verbal impressions, not yet fully understood, can be dated. How can early nonverbal impressions be translated into verbal language? It is possible that translation is facilitated by the recording of the first words heard and other early perceived images in each hemisphere even before lateralization is consolidated. But even later, such a translation from the language of non-speech images into natural language is also necessary for a psychoanalytic session. A deep analogy arises with hypnosis, in which, apparently, the left hemisphere is switched off and the right hemisphere is more or less isolated (resembling a left-sided shock). It is necessary to find out whether the sexual interpretation of the symbolism of the right hemisphere is not imposed upon its webralization by the left, which is characterized by an orientation toward conscious sex.

A similar question arises: how does the subdominant (right) hemisphere use verbal symbols typical of the dominant (left) hemisphere? Even Jackson, who was the first to discover the contrast between the functions of the two hemispheres more than 100 years ago, noted that aphasics retain the ability to swear. Moreover, removing the censorship of the left hemisphere, which controls the “official” norms of speech behavior, contributes to the freer use of swear words. But uncensored (“unofficial” in the terms of M.M. Bakhtin) speech of the right hemisphere usually does not relate to the sexual sphere as such. The right hemisphere uses the corresponding words not in direct, but in figurative use, corresponding to that carnival right-hemisphere imagery of the “grotesque body”, which in relation to the square language of the crowd was studied by the same M.M. Bakhtin. In this regard, the role of the word for understanding the entire macrocosm through correspondence with the human body among the Dogon is of particular interest. The use of these same words only in the literal sense is characteristic of some special forms of sexual behavior (for example, among homosexuals), where the participation of left-hemisphere mechanisms is likely (the erotic role, in particular, as a type of perversion). More normal (obligatory in the folklore of some peoples) is the use of such words in two senses, reminiscent of the pun mechanism described by Freud.

The right hemisphere normally (when the left hemisphere is censored) is wordless, and this is where the origins of its creative potential lie. The eminent linguist Roman Jakobson drew attention to the peculiarities of Einstein’s thinking, which was based not on words, but on wordless images, undoubtedly right-hemisphere. Of particular interest is the fact that already in adulthood, Einstein wanted to find such musical and color images (clearly related by their very nature to the sphere of the right hemisphere) that would correspond to his physical and geometric ideas; according to L.S. The term, corresponding work in his studio in New York was carried out by Einstein together with Bute, who later gained fame as a film director. It is also interesting to pay attention to the peculiarities of speech development (or more precisely, early underdevelopment) of Einstein. Even at the age of 9, Einstein used the words of a child's language; later he had difficulty learning to read. In retrospect, Einstein himself saw in his slow speech development one of the reasons that facilitated his discovery of the foundations of the theory of relativity: he said that he understood space and time in a new way precisely because he learned to use the words “Raum” and “Zeit” only at that age , when other young people have been saying them for a long time, as a rule, without thinking about their meaning, received in ready-made form when learning the language. As a problem for the psychological and biographical history of linguistics of the 20th century. It should also be noted that there is a probable connection between the early illness of N.S. Trubetskoy, which led to aphasia and agraphia with a subsequent depressive state (indicating the predominance of the right hemisphere), with the geometric orientation of the classification types of phonological systems he later proposed (his continued studies in musicology are also indicative).

The censorship of the left hemisphere in some cases must be removed (inhibited) to enhance or at least ensure creative imaginative activity. Connected with this is a clear negative attitude towards psychoanalysis by major literary artists. Everyone is familiar with Nabokov's oft-repeated attacks on the Viennese school. It would be worth devoting a special psychoanalytic study to clarifying the reasons for this hostility of the author of “Lolita” (a Freudian interpretation of which naturally suggests itself) towards Freud. Let me give you one example from my own memories. Once I asked A.A. Akhmatov, why she is so hostile to psychoanalysis. To this she answered me that if she had undergone a course of psychoanalysis, art would have been impossible for her. I supported her thought by referring to two letters from Rilke written on January 24, 1912. At this time, a friend of Nietzsche, Rilke and Freud, Lou Andreas-Zalome, persuaded the poet to undergo a course of psychoanalysis; He answered her that this would only be possible if he did not write anything else. After listening to my retelling of Rilke’s letter, Akhmatova remarked: “Well, you see, it means I was not mistaken. This happens to me sometimes."

The conflict between stereotypical psychoanalytic therapy and poetic creativity underlies the plot of Salinger's cycle of stories about the poet Shimura. His hero, having undergone a course of psychoanalysis at the insistence of his bourgeois relatives, commits suicide. After the creative imaginative function of the right hemisphere is inhibited due to the inclusion of psychoanalytic verbalization, among the various functions of this hemisphere, the depressive - destructive one - wins. Salinger's plan clearly contrasts psychoanalytic clinical practice in its vulgarized form with poetic creativity, among whose representatives Salinger is inclined to include Freud, but not his epigones. It is curious that in one of the letters to his fiancée, Freud himself wrote that he hoped to achieve in science what he failed to achieve in poetic experiments (Einstein also spoke about himself in a similar way, believing that he could fully use his boundless imagination in physics, not in art). Freud’s “visual curiosity,” noted by Erik Erikson, which allowed the founder of psychoanalysis to penetrate the dreams and memories of his patients even before the introduction of final verbal formulations, undoubtedly indicates the presence of this right-hemisphere component in Freud’s own intuition (for its study, Freud’s introspection in a letter to Fliess about his "both left hands"). This intuition was lacking in many of his followers (of course, Jung stands apart, who did a lot for a deep understanding of visual archetypes, despite the controversial and often fantastic nature of the verbal interpretations he proposed). Freud's greatest achievements (in the study of dreams and wit) are associated precisely with the manifestation of this intuition. It seems to me that Freud’s artistic intuition is also reflected in his judgments about art, such as the remark cited in Reik’s memoirs about Dostoevsky’s excessive fascination with pathological cases.

Among the examples illustrating the complementarity (in Bohr’s sense) of psychoanalytic verbalization and creative figurative processing of complexes censored by the left hemisphere (as the representative of society in the brain), I will cite the biographical background of Herman Hesse’s “Steppenwolf.” Let me remind you of the sequence of basic facts. Hesse, who suffered from severe depression for several years, began undergoing psychoanalysis immediately after the end of the first war. His life situation became increasingly aggravated, relief did not come, and his neurosis intensified. This circle of depressive experiences is expressed in a tragic and artistically crystallized form by Hesse in the later published poem “Steppenwolf.” But only artistic sublimation in the wonderful novel of the same name brought Hesse liberation from suffering. Then that enlightened view of the world arises, which is inherent in the late Hesse. Creativity turned out to be the completion of the healing process begun by psychoanalysis. The clear construction of the entire work as a description of the author’s experiments in verbalization of the past, partially similar to psychoanalytic ones, was the basis of Zoshchenko’s book “Before Sunrise.” After writing it, Zoshchenko said in my presence in 1943 that he managed to get rid of the melancholy that had tormented him all his life; he wanted to use the book to make this method publicly available.

Returning from fiction to science, in conclusion I will quote the words of one prominent physicist who became acquainted with the problems of functional asymmetry. According to him, the essence is to achieve perfect harmony between right and left. I think this is the modern form of E. Sapir’s thought about the normal functioning of the unconscious.

Ivanov V.V. The unconscious, functional asymmetry, language and creativity. Unconscious. Collection. - Novocherkassk, 1994, pp. 168-173

ASSESSMENT OF FUNCTIONAL ASYMMETRY USING DIFFERENT METHODOLOGICAL APPROACHES

Published in 2015, BIOLOGICAL SCIENCES, Issue August 2015 | No comments yet

Anisimova N.V.

Postgraduate student of the Department of Biology and Fundamentals of Medical Knowledge of the Chuvash State Pedagogical University named after I.Ya. Yakovleva, Cheboksary

ASSESSMENT OF FUNCTIONAL ASYMMETRY USING DIFFERENT METHODOLOGICAL APPROACHES

annotation

The purpose of this work is to assess functional asymmetry (FA) using N.N. Bragina and T.A. Dobrokhotova and the Edinburgh questionnaire. The study involved 37 schoolchildren aged 7 to 16 years. According to the results obtained using the methods of N.N. Bragina and T.A. Dobrokhotova to determine manual asymmetry, 30 schoolchildren are right-handed, 4 are left-handed and 3 are ambidextrous. According to the results of the Edinburgh testing, it was revealed that 31 schoolchildren have a leading right hand, 5 schoolchildren are left-handed and 1 is ambidextrous. The results of the correlation analysis show incomplete consistency between the indicators that determine physical activity using different methods.

Key words: functional asymmetry (FA), motor asymmetry, sensory asymmetry, asymmetry coefficient, “handedness”.

Anisimova NV

The graduate of department of biology and basic medical knowledge Chuvash state pedagogical university named by IY Yakovlev, Cheboksary

THE FUNCTIONAL ASYMMETRY ASSESSMENT BY DIFFERENT METHODS

Abstract

The purpose of this research is the functional asymmetry assessment by means of Edinburgh test and Bragina and Dobrohotova tests. Functional asymmetry research was held among 37 schoolchildren in age from 7 to 16. According to the results the padding block questions development by Bragina and Dobrohotova, 30 students are right-handed, 4 are left-handed and 3 are the ambidexters. , we have identified by the Edinburgh questionnaire, that 31 students have the leading right hand, 5 students are left-handed and 1 is the ambidexter. The results of correlation analysis show the partial coherence between FA indexes.

Keywords: functional asymmetry of brain, motor asymmetry, sensory asymmetry, index of asymmetry, handedness.

Relevance of the problem under study. The most important manifestations of FA are structural and functional differences between the left and right hemispheres of the human brain [8]. FA manifests itself in the form of pronounced specificity of information processing, reactivity and cognitive sphere in people with dominance of the right or left hemisphere [7]. To date, science has used two approaches to assess interhemispheric differences: the method of determining “handedness” through a survey (Edinburgh test) [11], and the method of actively identifying motor and sensory asymmetry by N.N. Bragina and T.A. Dobrokhotova [1]. The Edinburgh test is widely used in the world: it is used in the study of behavior [4], emotions [10] and as a preliminary test for selecting participants in neuroimaging studies [3]. Tests to determine the leading limbs and leading eye were used to assess the influence of brain lateralization on intelligence and mathematical abilities [9], to study the adaptive capabilities and physical development of boys and girls, as well as the formation of stress resistance of the body [2], [5]. It follows that both methods are widely represented in modern scientific literature, but we have not found any work that would evaluate the relationship between the results of testing functional asymmetry of the brain using the Edinburgh test and tests for determining motor and sensory asymmetry. Based on this, the purpose of our work is to assess functional asymmetry using N.N. Bragina and T.A. Dobrokhotova and the Edinburgh questionnaire.

Materials and research methods. The study involved schoolchildren from the Municipal Budgetary Educational Institution “Secondary School No. 31 with in-depth study of individual subjects” in Cheboksary, aged from 7 to 16 years, a total of 37 students. The average age was 12±0.4 years.

At the first stage of the study, schoolchildren answered questions from the Edinburgh test [11]. At the same time, their parents were responsible for children under 13 years of age. The Edinburgh questionnaire, adapted by us for schoolchildren, consists of fourteen questions about the preference for using the right or left hand when performing certain actions, such as writing, drawing, sewing, combing hair, brushing teeth, using a spoon or fork, etc. (Table 1).

Table 1 – Questionnaire for students

To determine manual and sensory asymmetry, N.N. tests were used. Bragina and T.A. Dobrokhotova [1].

Functional studies were carried out in the first half of the day, under conditions that meet the hygienic requirements for educational institutions [6]. The study complied with the ethical requirements set out in the Declaration of Helsinki.

The functional asymmetry coefficient was calculated based on answers to the Edinburgh questionnaire using formula (1):

Formula 1),

where H is the coefficient of functional asymmetry, X(i,R) and X(i,L) is the number of “+” signs in the “Right hand” and “Left hand” columns, respectively.

The coefficient of manual asymmetry (CMA) was determined according to formula (2):

formula (2),

where KMA is the coefficient of manual asymmetry, Nп is the number of actions performed by the right hand, Nт is the number of proposed tests.

The sensory asymmetry coefficient was calculated using formula (3):

formula (3),

where Nп is the number of actions performed by the right side of the body, Nт is the number of tests offered.

The total asymmetry is the sum of the KMA and SA coefficients (formula (4)).

formula (4),

where OA is general asymmetry, KMA is the coefficient of manual asymmetry, SA is sensory asymmetry.

Statistical processing of the study results was carried out using the Spearman correlation coefficient.

Research results and discussion. The frequency of occurrence of answer options for Edinburgh test questions is presented in table. 2.

Table 2 - Manual preferences revealed by the results of the Edinburgh test

As follows from the data given in Table 2, students perform most actions with their right hand.

Having analyzed the results obtained during testing using the Edinburgh questionnaire, we came to the conclusion that the majority of children who took part in the study have a pronounced predominance of the right hand: the average value of the asymmetry coefficient is 83.8%, the proportion of schoolchildren with a dominant right hand was 83.8%, with a preference for the left hand when writing and performing various types of work - 13.5%, using both hands with equal success - 2.7%. The distribution of the values ​​of the asymmetry coefficient calculated according to formula 1 is presented in Fig. 1.

Rice. 1 – Individual profiles of “handedness” based on answers to questions in the Edinburgh questionnaire (from left to right – X(i,R), X(i,L), H).

In the course of analyzing tests for motor asymmetry, we found that the majority of students perform tasks with their right hand (83.8% of cases), and the left hand was dominant in only 13.5%. In the course of analyzing the results of tests to identify sensory asymmetry, we found that for the majority of students the leading eye is the right eye (59.5%), and the left is only for 40.5% of students, in 81.1% of cases the leading ear is right.

Based on the coefficient of manual asymmetry, we determined that two children (5.4%) had almost complete left-handedness, the other two schoolchildren had strong left-handedness. The number of ambidextrous people was 3 (8.11%), and the proportion of children who had pronounced right-handedness was 9 (24.32%). In terms of manual asymmetry, the majority of schoolchildren we examined (21 or 56.76%) were strongly right-handed, although we did not find any schoolchildren who performed all tests with their right hand and had a dominant right leg.

The severity of sensory asymmetry was 32.97%. The left sensory fields were dominant in 8 (21.61%) children. The predominance of sensory flows on the right was noted in 29 (77.92%) schoolchildren.

The average value of complete asymmetry was 42.48%: 2 (5.4%) schoolchildren with almost complete left-handedness, 2 (5.4%) with strong left-handedness, 2 (5.4%) ambidextrous, 9 (24.32%) with pronounced right-handedness and 22 (59.46%) with strong right-handedness.

The main objective of our work is to study the relationship between the results of testing functional asymmetry of the brain using various methods by calculating the Spearman correlation coefficient.

The results of the analysis of the relationship between the H coefficient of the Edinburgh questionnaire, on the one hand, and the coefficients of motor and sensory asymmetry according to the method of N.N. Bragina and T.A. Dobrokhotova are presented in Fig. 2.

Rice. 2 – Correlation connections between the coefficient N and the coefficient of motor asymmetry (A), the coefficient of sensory asymmetry (B)

From the data in Figure 2 it follows that there is a statistically significant correlation between the H coefficient and the motor asymmetry coefficient (R = 0.58; P <0.05); We did not find such a connection in the case of sensory asymmetry (R=0.18, P>0.05). This indicates that the results of testing using the Edinburgh questionnaire are not sufficient to obtain a complete picture of functional asymmetry of the brain.

Summary.

The data we obtained indicate left hemisphere dominance in schoolchildren, both according to the results of a study using the methods of Bragina and Dobrokhotova, and according to the results of the Edinburgh questionnaire. Although the coefficient of manual asymmetry and the coefficient of handedness are related to each other, the dominance of the right hand, revealed by the results of answers to questions, and the nature of sensory asymmetry are not consistent with each other. In addition, we noted individual cases of discrepancy between answers to the questionnaire and real preference for the right and left hands. Based on this, we consider it necessary to conduct additional research to improve the Edinburgh questionnaire.

Literature

1. Bragina, N. N. Functional asymmetries of man / N. N. Bragina, T. A. Dobrokhotova. – 2nd ed. reworked and additional – M.: Medicine, 1988. – 237 p.
2. Lisova N.A. and others. The role of activation processes of the cerebral cortex in the formation of stress resistance in female students with different temperamental characteristics // Siberian Bulletin of Special Education. – 2015. – No. 2(15). – pp. 52-57.
3. Mikhailov, I.V. The significance of functional asymmetry in teaching complex purposeful bimanual movements / I.V. Mikhailov, P.V. Tkachenko // Modern high technology. – 2009. – No. 9. – P. 59–
4. Pankova N.B., Romanov S.V. Dynamics of behavioral manifestations and quantitative indicators of functional interhemispheric asymmetry in students during the school year // Scientific prospects of the XXI century. Achievements and prospects of the new century // III International Scientific and Practical Conference, Novosibirsk, August 15–16, 2014 – No. 3. Part 5. – Novosibirsk: International Scientific Institute “Educatio”, 2014. – P. 38–42.
5. Pulikov A.S. and others. Individual typological characteristics and features of the lateral phenotype in young men // Modern studies of social problems (electronic scientific journal). – 3013. – No. 1. URL: https://sisp.nkras.ru/e-ru/issues/2013.html.
6. SanPiN 2.4.2.2821-10 “Sanitary and epidemiological requirements for the conditions and organization of training in educational institutions” dated 03.03.2011.
7. Sychev, V. S. Functional asymmetry of the brain. Problems and prospects for solutions / V.S. Sychev // BBK 20 A 437. – P. 197.
8. Fokin, V.F. et al. Guide to functional interhemispheric asymmetry / V.F. Fokin // M.: Scientific world. – 2009. – 836 p.
9. Khokhlov N.A. Lateral signs, structural-level characteristics of intelligence and mathematical abilities / N.A. Khokhlov, M.S. Kovyazina // Magazine “Asymmetry”. Volume. – 2013. – T. 7. – No. 3. – pp. 32–52.
10. Aaron A. et al. Reward, motivation, and emotion systems associated with early-stage intense romantic love // ​​Journal of neurophysiology. – 2005. – T. 94. – No. 1. – pp. 327–337.
11. Oldfield RC: The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 1971 Mar; 9 (1) – pp. 97–113.

References

1. Bragina, NN Funkcional'nye asimmetrii cheloveka / NN Bragina, TA Dobrohotova. – 2nd ed. pererab. i dop. – M.: Medicina, 1988. – 237 s.
2. Lisova NA i dr. Rol' aktivacionnyh processov kory golovnogo mozga v formirovanii sressoustojchivosti u studentok s razlichnymi temperamental'nymi harakteristikami //Sibirskij vestnik special'nogo obrazovanija. – 2015. – No. 2(15). – S. 52-57.
3. Mihajlov, IV Znachenie funkcional'noj asimmetrii pri obuchenii slozhnym celenapravlennym bimanual'nym ​​dvizhenijam / IV Mihajlov, PV Tkachenko // Sovremennye naukoemkie tehnologii. – 2009. – No. 9. – S. 59–
4. Pankova NB, Romanov SV Dinamika v uchebnom godu povedencheskih projavlenij i kolichestvennyh pokazatelej funkcional'noj mezhpolusharnoj asimmetrii u uchashhihsja // Nauchnye perspektivy XXI veka. Dostizhenija i perspektivy novogo stoletija // III Mezhdunarodnaja scientific-prakticheskaja konferencija, Novosibirsk, 15–16 August 2014. - No. 3. Chast' 5. – Novosibirsk: Mezhdunarodnyj Nauchnyj Institut “Educatio”, 2014. – S. 38–42.
5. Pulikov AS i dr. Individual'no-tipologicheskaja harakteristika i osobennosti lateral'nogo fenotipa u junoshej // Sovremennye issledovanija social'nyh problem (jelektronnyj nauchnyj zhurnal). – 3013. – No. 1. URL: https://sisp.nkras.ru/e-ru/issues/2013.html.
6. SanPiN 2.4.2.2821-10 "Sanitarno-jepidemiologicheskie trebovanija k uslovijam i organizacii obuchenija v obshheobrazovatel'nyh uchrezhdenijah" from 03.03.2011.
7. Sychjov, VS Funkcional'naja asimmetrija mozga. Problemy i perspektivy reshenija / VS Sychev // BBK 20 A 437. – S. 197.
8. Fokin, VF i dr. Rukovodstvo po funkcional'noj mezhpolusharnoj asimmetrii / VF Fokin // M. : Nauchnyj mir. – 2009. – 836 s.
9. Hohlov NA Lateral'nye priznaki, strukturno-urovnevye harakteristiki intellekta i matematicheskie sposobnosti / NA Hohlov, MS Kovjazina // Zhurnal “Asimmetrija”. Tom. – 2013. – T. 7. – No. 3. – S. 32–52.
10. Aaron A. et al. Reward, motivation, and emotion systems associated with early-stage intense romantic love // ​​Journal of neurophysiology. – 2005. – T. 94. – No. 1. – pp. 327–337.
11. Oldfield RC: The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 1971 Mar; 9 (1) – pp. 97–113.

Current issues of functional interhemispheric asymmetry and neuroplasticity

Edited by Illarioshkin S.N., Kobrin V.I., Fokin V.F. M.: Scientific world, 2008. 808 p.

This collection of materials from the conference “Current issues of functional interhemispheric asymmetry and neuroplasticity” is devoted to two fundamental problems of neurobiology and medicine. The problem of functional interhemispheric asymmetry is inherently multidisciplinary; it brings together specialists working in various fields of biology, medicine, psychology and, of course, neuroplasticity. This conference is taking place in a memorable year for the scientific community - the 80th anniversary of the creation of the Brain Institute, which is currently included in the Scientific Center for Neurology of the Russian Academy of Medical Sciences. Apparently, it would not be an exaggeration to say that, starting from the 80s of the last century, the Brain Institute became a scientific and organizational center for the study of functional interhemispheric asymmetry in our country. This was facilitated by the creation by Academician of the Russian Academy of Medical Sciences O.S. Adrianov of the multidisciplinary section at the Physiological Society of the USSR for the study of the organization and lateralization of cerebral functions. The Directorate of the Scientific Center for Neurology of the Russian Academy of Medical Sciences actively supports this area of ​​research. Currently, original studies of functional interhemispheric asymmetry are being conducted at the State Classical Academy named after. Maimonides, as well as in many scientific groups in our country. The volume of publications on the problem of asymmetry is growing all over the world. In 2004, the “Reader on Functional Interhemispheric Asymmetry” was published, and at the beginning of 2009, the “Guide to Functional Interhemispheric Asymmetry” will be published. For a whole year now, the electronic magazine “Asymmetry” has been published on the website https://www.j-asymmetry.com/, which is currently registered by the Federal Service for Supervision of Mass Communications of the Russian Federation. Since 2001, scientific conferences on the issues of functional interhemispheric asymmetry and brain plasticity have been regularly held. Russia, in terms of its scientific traditions, originality of approaches, and intensity of research work, occupies one of the leading positions in the world in the study of functional interhemispheric asymmetry, evidence of which is the present edition of the conference materials.

CONTENT

Section 1. INTERHEMISPHERE ASYMMETRY

Morphofunctional organization of interhemispheric asymmetry

Aidarkin E.K. Dynamics of functional interhemispheric asymmetry in the process of implementing a sensorimotor reaction

Aidarkin E.K., Pavlovskaya M.A. The role of functional interhemispheric asymmetry in the formation of sensorimotor integration under conditions of visual and auditory sequential masking

Askerov F.B., Movsumov G.D., Ibragimova S.A. The influence of audiogenic stress on the interhemispheric content of water-soluble proteins in stress-resistant and stress-unresistant animals

Badalyan S.A., Sargsyan V.A. Morphological manifestation of asymmetry of neural populations - sources of reorganized vestibulothalamic projections

Bogolepova I.N., Malofeeva L.I. Morphological criteria for interhemispheric asymmetry of the cortical formations of the brain in men and women

Borisova L.M., Bogolepova I.N. Analysis of the sizes of neurons in the cortical fields of the insular region in the right and left hemispheres of the brain of women

Wiesel T.G. Cerebral organization of speech function depending on the characteristics of interhemispheric asymmetry of the brain.

Geodakyan V.A. Genomic imprinting is a myth and double dichronism.

Krotenkova M.V., Konovalov R.N., Bogolepova I.N., Malofeeva L.I., Agapov P.A. Principles of structural asymmetry of the speech motor center of the human brain (cytoarchitectonic and MRI studies).

Leutin V.P. Functional asymmetry of the central regulation of respiration under the influence of intermittent normobaric hypoxia.

Mikheev V.V., Karpova I.V., Shabanov P.D. Effect of unilateral cortical spreading depression on the behavior of mice with a defensive behavior pattern.

Nikolaeva E.I., Borisenkova E.Yu. Handedness: phantom or reality?

Novoselova N.Yu., Moskvin A.N., Reichardt B.A., Sapronov N.S., Ivanova V.P. Lateralization of the effects of superoxide dismutase and NO synthase inhibitor on lipid peroxidation in the brain of rats under hyperbaric oxygenation.

Ponomareva N.V., Krotenkova M.V., Konovalov R.N., Shcheglova N.S., Mitrofanov A.A. Interhemispheric disintegration and its dependence on the size of the corpus callosum during normal aging.

Pugach V.N., Kabaeva V.M. Functional asymmetry of the brain: ambidexterity and ambitcerebrality, new trends.

Smyk A.V., Ershov O.V., Abramov V.V. Functional asymmetry of the peripheral part of the immune system and its relationship with functional asymmetry of the central nervous system.

Sollertinskaya T.N., Shorokhov M.V. Neuroplasticity. Features of neuropeptide regulation of functional interhemispheric brain asymmetry in the ascending series of mammals.

Stashkevich I.S., Kulikov M.A. Functional interhemispheric asymmetry and the implementation of various stages of food-procuring behavior in rats.

Tereshchenko L.V., Molchanov S.A., Kolesnikova O.V., Latanov A.V. Possibility of determining the preferred hand in monkeys (Masaca mulatta) in a laboratory experiment.

Udalova G.L., Karas A.Ya. Spatial-motor asymmetry and plasticity of behavior in Myrmica rubra ants when switching from one type of motivation to another.

Khrenkova V.V., Zolotukhin V.V., Zolotukhin P.V. Features of the evoked activity of the symmetrical areas of the midbrain roof (RMC) of the frog in the dynamics of adequate and inadequate stimulation.

Chervyakov A.V. On the issue of asymmetry of cerebral blood flow.

Gutnik B., Kobrin V. The patterns of bimanual coupling among right handed young men and women.

Gutnik B., Penchev V., Pencheva S., Kobrin V., Vasil'eva E., Kravchenko A. Asymmetry of energy of resistance of a distal hand muscle in vivo.

Psychophysiological aspects of interhemispheric asymmetry

Akulina M.V. Features of interhemispheric brain asymmetry and physical development of schoolchildren aged 13-16 years old studying in schools of various types in Ryazan.

Arshavsky V. Population structure of functional interhemispheric asymmetry polymorphism.

Belasheva I.V., Polshakova I.N., Tereshchenko E.V. Individual styles of emotional response of girls and the profile of lateral organization of functions.

Berdichevskaya E.M., Khachaturova N.E. Stability of the upright posture of qualified shooting athletes during optokinetic testing taking into account vision asymmetry.

Bobrova E.V., Lyakhovetsky V.A., Bogacheva I.N., Chelnokova O.V., Skopin G.N., Borshchevskaya E.R. Features of interhemispheric interactions in the regulation of movements and posture.

Boravova A.I., Galkina N.S., Fokin V.F. Lateralization of the relationship between individual-typological personality indicators and brain energy metabolism in schoolchildren aged 12-13 years.

Botasheva T.L., Chernositov A.V., Rogova N.A., Zavodnov O.P., Yakina I.V. Psychological status of combatants from the position of the asymmetrically dominant principle of organization of psychophysiological functions.

Endolov V.V., Muravyova M.S. Dynamics of functional interhemispheric asymmetry of the brain of primary school children during the learning process.

Buduk-ool L.K. Interhemispheric functional asymmetry of the brain during adaptation to learning of students of different ethnic groups living in Siberia.

Budyka E.V., Efimova I.V. Functional interhemispheric asymmetry as one of the biological prerequisites for individual differences in cognitive processes.

Gronskaya A.S., Bugaets Ya.E. Finger dermatoglyphics in studies of manual motor asymmetry.

Efimova I.V., Budyka E.V. Motor and sensory asymmetries at the initial stage of learning to swim.

Karazaeva A.Yu., Razumnikova O.M., Leutin V.P. Differences in creative and intellectual abilities depending on the lateral phenotype in marginalized groups.

Karatysh T.V. Gender analysis of the formation of bimanual movements in early ontogenesis in children with different asymmetry profiles.

Kolesnikova O.V., Tereshchenko L.V., Kachalova L.M., Latanov A.V. The influence of the functional asymmetry profile on eye movement parameters during reading.

Maler M.V., Kudrya O.N., Fomina E.V. Lateral phenotype and adaptability of the cardiovascular system of athletes when performing dosed loads.

Malov A.G., Ovchinnikova E.S. Heterogeneity of the phenomenon of mirror writing in children with different profiles of functional asymmetry.

Oknina L.B., Kuznetsova O.A. Features of interhemispheric interaction with different degrees of concentration of attention on a task in healthy subjects (analysis of equivalent dipole sources of the ROOO component of the acoustic evoked potential).

Polevaya S.A., Khomyakova M.I. The influence of head rotation on interhemispheric relations during lateralization of a dichotic stimulus.

Radionova E.A. Asymmetry in human perception of a moving sound source (sound image).

Rozhnova K.S. Features of the functional activity of the brain of adolescents with different levels of physical activity.

Rusalova M.N., Kislova O.O. Human EEG asymmetry in recognizing speech emotions.

Slavutskaya M.V., Moiseeva V.V., Semina T.K., Shulgovsky V.V. Interhemispheric asymmetry in saccade programming from memory.

Tynalieva B.K., Saidyldaeva A.B. Interhemispheric asymmetry as a factor of adaptation to high-altitude hypoxia.

Kholmansky A.S., Dashchinskaya T.N. Resource of functional brain asymmetry.

Shvaiko S.E., Dmitrotsa E.R., Kachinskaya T.V., Shelepenko A.I. Correlation connections of evoked potentials of the cerebral cortex of persons with manual asymmetry during cognitive activity

Shcheglova N.S., Ponomareva N.V. The influence of interhemispheric asymmetry of functional activity and energy metabolism of the brain on the level of anxiety and autonomic indicators.

Shchimko I.A., Fokin V.F. Modulation of energy consumption of the left and right hemispheres of the brain during training of concentration in children 10-11 years old.

Yunusova S.T., Gerasimova Yu.V. Study of functional asymmetry in twins.

P. V. Wackermann, M. Grellet, J. C. Pereira. Musical ability, mapping of brain electrical activity and acoustic analysis of the voice.

Clinical studies of interhemispheric asymmetry

Abramov S.V., Abramova T.Ya., Shishkova K.V., Sizikov A.E., Kozhevnikov V.S., Abramov V.V. Comparative characteristics of the T-cell component of the immune system in donors and patients with rheumatoid arthritis with different functional interhemispheric asymmetry (FMA) of the brain.

Borisova N.V., Donskikh T.A., Voronkova Yu.A., Petrova E.A., Vizel T.T., Skvortsova V.I. Restoration of impaired functions with additional activation of the affected and intact cerebral hemispheres in patients in the acute period of ischemic stroke.

Vasilyeva V.V., Chernositov A.V., Bondarenko Yu.E. Functional interhemispheric asymmetry in the formation and functioning of the gestational dominant.

Gordeev S.A., Shvarkov S.B. Features of changes in interhemispheric EEG asymmetry in patients with generalized anxiety disorder and patients with panic attacks.

Endolov V.V., Muravyova M.S., Birchenko N.S. Individual profile of the lateral organization of brain functions and the likelihood of developing idiopathic scoliosis in children.

Zhavoronkova L.A., Maksakova O.A., Zharikova A.V., Flerov K.S. Features of disturbances of interhemispheric EEG asymmetry in post-traumatic Korsakoff syndrome and rehabilitation approaches for their correction.

Kvashchenko E.I., Fokin V.F. The effect of the combination of piracetam and cinnarizine on the clinical and physiological characteristics of patients with initial signs of cerebral circulatory failure.

Ioffe M.E., Chernikova L.A., Muratova P.M., Katsuba N.A., Kulikov M.A. Interhemispheric asymmetry in learning postural tasks in the process of post-stroke rehabilitation.

Klimenko L.L., Deev A.I., Protasova O.V., Soyustova E.L., Fokin V.F. Reduction of the interhemispheric neurophysiological gradient in rheumatic and endocrine diseases.

Krylov O.E., Zemlyanaya A.A., Kovyazina M.S., Kalinin V.V. The influence of indicators of lateralization of sensorimotor functions and the focus of epileptic activity on the characteristics of the course of epilepsy.

Krylov O.E., Zemlyanaya A.A., Kovyazina M.S., Kalinin V.V. Epilepsy as a model for studying the connection between psychopathological symptoms and interhemispheric interaction (using the example of one clinical case).

Lebedeva I.S., Kaleda V.T., Abramova L.K., Barkhatova A.N., Korovaitseva G.K., Lizheiko T.V., Golimbet V.E. Interhemispheric asymmetry of neurophysiological markers of cognitive abnormalities in schizophrenia: from clinical to molecular genetic aspects.

Levashov O.V. Visual “pollution” of the environment and the problem of dyslexia (the influence of “information asymmetry” of the environment).

Lushchekina E.A., Lushchekin V.S., Podreznaya E.D., Gorina I.S. Profile of lateral asymmetry, type and maturity of the nervous system in children with neurotic disorders.

Nabieva T.N. The influence of perinatal pathology on the development of a dominant hand.

Nikolaenko N.N. Interhemispheric interaction in normal conditions and in the treatment of mental illnesses.

Opolinsky E.S., Arkhipov B.A., Dairova R.A., Makeenko S.V., Ivanitskaya L.N. Features of interhemispheric asymmetry in normal ontogenesis and its transformation in some variants of local brain lesions.

Orlova V.A., Savina T.D., Efanova N.N., Gubsky L.V., Kupriyanov D.A., Anisimov N.V. Asymmetry of subcortical nuclei (MRI data) and memory characteristics (semantic aspect) in families of patients with schizophrenia.

Rozhkova L.A. Interhemispheric EEG coherence in primary school children with perinatal developmental disorders.

Smyk A.V., Ershov O.V., Abramova T.Ya., Nepomnyashchikh V.M., Demina D.V., Leonova M.I., Abramov V.V. The effectiveness of body-oriented psychocorrection of alexithymia in patients with bronchial asthma depending on the functional asymmetry of the brain.

Teleshova V.A., Rumyantseva M.V., Zavadenko N.N. Interhemispheric asymmetry in the involvement of areas of the cerebral cortex in the process of visual recognition in children with dyslexia according to EEG data.

Urokov S.V., Dobrokhotova T.A. Psychopathological disorders in the structure of epileptic seizures and interhemispheric asymmetry.

Fokin V.F., Ponomareva N.V., Krotenkova M.V., Konovalov R.N., Sergeeva A.N., Tanashyan M.M., Lagoda O.V. Functional interhemispheric asymmetry during activation of mnestic processes in patients with chronic cerebrovascular diseases.

Chigaleychik L.A., Baziyan B.Kh., Damyanovich E.V., Teslenko E.L. Study of visual-motor coordination in lateralized forms of Parkinson's disease.

Chuprikov A.P., Chuprikova E.G., Dvirsky A.A., Sinitsky I.V. Features of the lateral characteristics of children and adolescents with epilepsy.

Chuprikova E.G., Dvirsky A.A., Chuprikov A.P., Sinitsky I.V. Clinical features of left- and right-handed children and adolescents with epilepsy.

Sharova E.V., Gavrilov V.M., Zaitsev O.S., Anzimirov V.L., Sokolovskaya I.E., Kopotaeva M.B., Novikova M.R. Changes in the functional activity of the brain under the influence of rhythmic TMS in normal conditions and in post-traumatic depression of consciousness.

Shein A.P., Skripnikov A.A. EEG correlates of functional interhemispheric asymmetry in the consequences of stroke and severe traumatic brain injury in the conditions of vasoactive cranioosteoplasty.

Section 2. CURRENT ISSUES IN NEUROPLASTICITY

Morphofunctional manifestations of neuroplasticity

Abushov B.M. Features of reparative changes in neurons of some somnogenic formations of the rat brain during 24-hour total sleep deprivation.

Averina K.V., Mednikova Yu.S. Changes in the parameters of spontaneous and evoked impulses of cortical neurons during short-term hypothermia.

Ambartsumyan L.E., Khalaji N., Manukyan L.P., Chavushyan V.A., Badalyan S.A., Sargsyan V.A., Sargsyan J.S. Plasticity of neurons in the lateral vestibular nucleus of Deiters under conditions of unilateral delabyrinthation.

Amunts V.V., Antyukhov A.D., Sveshnikov A.V. Morphometric features of neurons in the anterior dorsal and reticular nuclei of the thalamus of the male brain.

Andreasyan A.S. Effect of stimulation of the hypothalamus with an alternating electromagnetic field on the plasticity of the damaged spinal cord.

Badalyan S.A. “Paired cells” as a morphological criterion for assessing neuroplastic variability in the central nervous system.

Badalyan S.A., Sargsyan V.A. Morphological manifestation of asymmetry of neural populations - sources of reorganized vestibulothalamic projections.

Baibakov S.E., Vlasov E.A. Morphometric characteristics of the brain according to magnetic resonance imaging.

Berezhnaya L.A. Structural plasticity of neurons in the thalamic nuclei.

Bogolepov N.N. The role of dendritic spines in the plasticity of synapsoarchitecture of the cerebral cortex.

Bogolepova I.N., Antyukhov A.D. Morphometric features of the lateral nucleus of the amygdala of the adult brain.

Bogolepova I.N., Sveshnikov A.V. Features of the structure of grooves and convolutions on the medial surface of the cerebral hemispheres in men.

Kirik O.V., Zelenkova N.M., Korzhevsky D.E. Selective detection of neuroblasts in the subventricular proliferative zone of the telencephalon.

Mednikova Yu.S., Pasikova N.V., Rogal A.V., Kopytova F.V., Khudoerkov PM Morpho-functional basis for the diversity of cortical neurons.

Meliksetyan I.B., Abrahamyan S.S., Sahakyan I.K., Melkonyan N.N., Nazaryan O.A., Mkrtchyan O.A., Avetisyan Z.A. Early manifestations of the morpho-functional state of the cellular structures of the brain of rats under immobilization stress.

Meliksetyan I.B., Sargsyan S.T., Minasyan S.M., Eghiazaryan M.L. Morpho-functional features of the Deiters nucleus in labyrinthectomized rats after vibration exposure.

Mukhina I.V., Khaspekov L.G., Kazantsev V.B., Korotchenko S.A., Koryagina E.A., Obukhova L.M., Vedunova M.V. The med64 multielectrode system in the study of synaptic plasticity in cultured dissociated hippocampal cells.

Mukhina Yu.K., Fedorov A.A., Khrenov A.I., Stekolnikova S.G. Neurons of the lateral and magnocellular basal nuclei of the amygdala in the adult brain are positive for the calcium binding protein calretinin.

Obukhov D.K., Kryuchkov V.I., Obukhova E.V., Pushchina E.V. The effect of matroclinic (maternal) heredity on the morpho-functional organization of the brain.

Orzhekhovskaya N.S. Sexual differences in the cyto-glioarchitecture of area 46 of the frontal region of the human brain.

Orlyanskaya T.Ya., Ustinova T.I., Chizhova S.V., Krupkina V.S., Ilchenko A.V. Assessment of the plasticity of brain structures under exogenous influences based on a comprehensive assessment of the morphological characteristics of neurons and glia.

Petrov A.V., Fedorov V.P., Ilyicheva V.N., Sokolov D.A., Terezanov O.Yu. Heterochrony and heteromorphism of the post-radiation period in the central nervous system after exposure to ionizing radiation in different doses.

Podrezova E.P., Sosunov A.A., McKhan G.-II, Shikhanov N.P., Khovryakov A.V., Balashov V.P., Podrezov M.A., Sosunov S.A., Sruglyakov P. .P. Anomaly of mitotic division of reactive astrocytes as a cause of the formation of polyploid and aneuploid cells.

Popova E.N., Kotik E.V. Changes in the structure of the cerebral cortex during emotional stress and caudate hemorrhagic stroke in rats with different types of behavior.

Ryzhavsky B.Ya., Eremenko I.R., Matveeva E.P., Baranova S.N., Vasilyeva E.V., Uchakina R.V. Results of an experimental study of advanced brain development.

Salkov V.K., Khudoerkov P.M., Levchenkova V.D. The nature of changes in the morphometric parameters of field 17 of the cerebral cortex in children with perinatal damage to the central nervous system.

Sashkov V.A. Sexual characteristics of the morphology of individual brain structures in old rats in the process of learning and extinction of the conditioned reflex.

Stepanova I.P., Lysov P.K., Kargina A.S. Structural transformations of the optic nerve and its membranes in embryogenesis of humans and mammals.

Trukhachev A.N., Zuev V.T., Fedorov V.P. Morphofunctional state of the cerebral cortex under conditions of uneven electromagnetic irradiation.

Fetisov CO, Fedorov V.P. Morphometric characteristics of the posterior part of the thalamus in the initial stages under the influence of ionizing radiation in low doses.

Khudoerkov P.M., Mikhaenkova N.V., Gulevskaya T.S., Anufriev P.L. Quantitative neurohistological parameters in the perifocal zone of infarction of the precentral region of the human cerebral cortex.

Tsekhmistrenko T.A., Vasilyeva V.A., Shumeiko N.S., Chernykh N.A. Some features of structural transformations of the ensemble organization of the human cerebral cortex in ontogenesis.

Shevtsov V.I., Safonova G.D., Mushtaeva Yu.A. Structural transformations in the area of ​​spinal cord injury with different biomechanical conditions of the spine.

Morphochemical manifestations of neuroplasticity

Vlasenko A.G., Minton M.A. Assessment of the regional level of aerobic glycolysis in the human brain under conditions of rest and activation load using positron emission tomography.

Gershtein L.M., Korneva I.M. Morphochemical differences in parietal cortex neurons caused by a response to hyperactivity of the dopaminergic system.

Gundareva O.P., Fedorov V.P., Afanasyev R.V., Terezanov O.Yu. The state of nucleic acids in neurons of the cerebellar cortex in the early stages after low radiation exposure.

Dovedova E.L., Khrustalev D.A., Moskvitina T.A. Modeling of dopamine pathology in brain structures with the introduction of exogenous deoxyphenylalanine (L-DOPA).

Kozhechkin S.N. Interaction of ethanol and (Beta-endorphin on the membrane of neurons in the rat frontal cortex. Microelectrophoretic study).

Kolbaev S.N. Effect of exogenous glutamine on the excitability of cultured rat hippocampal neurons.

Korzhevsky D.E., Sukhorukova E.G., Kirik O.V. Use of immunocytochemical markers to identify activated microglia and macrophages in the brain.

Lukin S.V., Dzhanibekova N.A., Lozier E.R., Stelmashuk E.V., Trofimova L.K., Graf A.V., Zorov D.B., Sokolova N.A., Isaev N. .TO. The effect of acidosis and amiloride on the viability of neurons in the cerebral cortex at different periods of cultivation.

Manvelyan L.R., Petrosyan T.R., Gevorkyan O.V., Meliksetyan I.B. Effect of unilateral pyramidotomy and bacterial melanin administration on corticofugal plasticity in adult rats.

Mukhin E.I., Mukhina Yu.K., Zakharova E.Zh. The role of cholinergic and noncholinoreactive brain structures in plastic cognitive mechanisms in psychoorganic symptoms of the associative thalamo-parietal level of integration.

Petrosyan T.R. Activity of spinal cord motor neurons in rats after unilateral pyramidotomy and exposure to bacterial melanin.

Pushchina E.V., Fleishman M.Yu., Tsygankov V.I., Obukhov D.K., Timoshin S.S. Effect of dermorphins on neuronal plasticity and proliferative activity of NO-producing neurons in the brain of juvenile Amur sturgeon Acipencer schrenki.

Rossokhin AB Point mutation a413c of the potassium channel kvl.3 dramatically affects the binding of verapamil and its derivatives. Molecular modeling.

Salmina A.B., Okuneva O.S., Malinovskaya N.A., Morgun A.V., Fursov A.A., Zykova L.D., Bolshakova E.V., Mikhutkina S.V. Dynamics of changes in ADP-ribosyl cyclase activity in brain cells in the early postnatal period.

Salmina A.B., Okuneva O.S., Taranushenko T.E.. Zykova L.D., Fursov A.A., Malinovskaya N.A., Mikhutkina S.V., Morgun A.V. Neuron-astroglial relationships mediated by the activity of NAD+-converting enzyme in perinatal hypoxic-ischemic brain damage.

Sargsyan S.T., Minasyan S.M., Meliksetyan I.B., Chavushyan V.A., Sargsyan J.S., Galoyan A.A. Protective effect of a proline-rich hypothalamic neurohormone on the activity of vestibular neurons under conditions of unilateral afferent deprivation.

Sgibneva N.V., Fedorov V.P., Afanasyev R.V. The state of the protein system of neurocytes after general gamma radiation in low doses.

Sergutina A.V. A histochemical approach to the study of the metabolism of neurotransmitters and proteins in the CA 1 and CA 3 fields of the hippocampus of the brain of August rats, predisposed to emotional stress.

Stelmashuk E.V., Isaev N.K. The influence of paraquat and pH on the survival of cerebellar granule neurons at different periods of cultivation.

Khudoerkov PM, Voronkov D.N. Features of immunohistochemical changes in tyrosine hydroxylase in the dopaminergic structures of the midbrain of Wistar rats when modeling the hyper- and hypofunction of dopamine metabolism.

Chumasov E.I., Korzhevsky D.E., Petrova E.S. Distribution of synaptic terminals in the rat heart (immunocytochemical study).

Shugalev N.P., Stavrovskaya A.V., Olshansky A.S., Yamshchikova N.G., Miroshnichenko E.V. Aftereffects of pain and immobilization stress on the motor activity of rats against the background of the introduction of neurotensin into the formations of the nigrostriatal system of the brain.

Physiological and clinical aspects of neuroplasticity

Avetisyan E.A., Petrosyan A.A. Electrophysiological study of the regulation of the activity of vago-sensitive neurons of the nucleus of the solitary tract by structures of the telencephalon.

Agaeva E.N. The influence of hypokinesia during the fetal period of pregnancy on general motor activity in white rat pups in the process of changing play activity.

Bazanova O.M. Individual characteristics of alpha activity and neurofeedback in the training of musicians.

Baziyan B.Kh., Ivanova M.E., Gordeev S.A., Ortmann V.V. Adaptation of the brain to a cortical visual prosthesis.

Vanetsian G.L., Pavlova I.V. Behavioral, autonomic and electrographic correlates of aversive behavior in cats during extinguishment of the orienting reflex to sound clicks.

Grigoryan K.M. Synaptic plasticity of neural elements of the spinal cord in hypoparathyroidism.

Gulevskaya T.S., Morgunov V.A. Adaptive changes in the arterial system of the brain in atherosclerosis and arterial hypertension.

Dikevich E.A., Fedotova E.Yu., Ponomareva I.V. EEG correlates of depression in patients with Parkinson's disease.

Damyanovich E.V., Baziyan B.Kh., Chigaleychik L.A., Sagalov M.V., Kumskova G.A. Assessment of the state of the oculomotor system in children 7-9 years old with attention deficit hyperactivity disorder.

Zimina S.V. The role of the dorsal raphe nuclei in the development of seasonal depression.

Iznak A.F., Iznak E.V. EEG correlates of “hypofrontality” in schizophrenia.

Morgun A.V., Taranushenko T.E., Salmina A.B., Borisova M.V., Bulova T.I., Okladnikova L.M., Kadricheva T.T., Malyutin O.A., Rykovanova T. .N. Selected clinical and biological features of malignant brain tumors in children.

Orlova T.V., Lyubimov S.I. On the localization of sources of somatosensory evoked potentials of the brain in humans.

Ponomareva N.V., Boykova T.V., Rogaev E.I. The influence of apolipoprotein E genotype on the functional activity of the brain during aging.

Poruchinskaya T.F. Spatial distribution of correlations in the alpha and beta ranges of the EEG, taking into account the level of functional mobility of nervous processes (gender differences).

Pustokhanova L.V., Kulesh A.A., Morozova E.M. Clinical features of cognitive impairment in ischemic stroke of hemispheric localization.

Ryabchikova N.A., Baziyan B.X., Polyansky V.B., Pletnev O.A. Saccades as a reflection of cognitive processes.

Salkov V.N., Levchenkova V.D., Sheinkman O.G. The state of neurodynamics in children with cerebral palsy according to neurophysiological studies of sleep and wakefulness.

Sokolova L.P., Borisova Yu.V., Tarabarina N.B., Vitko N.K. Features of neurometabolism in young and middle-aged patients with mild cognitive disorders.

Sufianova G.Z., Shapkin A.G., Usov L.A., Sufianov A.A., Klets O.P. Changes in SCP and slow electrical activity of the brain during intracerebroventricular administration of ATP.

Fedorova E.S. Analysis of the relationship between visuospatial intelligence and the magnitude of Poggendorff figure distortion.

Khudaverdyan D.N., Mnatsakanyan V.R., Chavushyan V.A., Avetisyan Z.A., Sargsyan J.S. Plasticity of hippocampal neurons under the conditions of aR(25-35) induced model of Alzheimer's disease and exposure to parathyroid hormone.

Chelyapina M.V., Sharova E.V., Zaitsev O.S. EEG correlates of activation of the dopaminergic system under the influence of amantadine (PC-Merz) in patients with severe traumatic brain injury.

Shmyrev V.I., Sokolova L.P., Borisova Yu.V., Vitko N.K. Functional disorders of brain neurometabolism as the main pathogenetic factor in the development of mild and moderate cognitive disorders.

Yurkova E.A. Blockade of the autonomic gastric plexus during surgical interventions on the stomach in an experiment.